When a doctor is found brutally murdered in the lurid section of London aptly named "Devil's Acre," even its most hardened residents are stunned. But shock soon turns to horror when Inspector Thomas Pitt discovers three more bodies with the same gruesome "calling card": a stab wound in the back and a rather inexpertly executed mutilation. As Pitt and his wife, Charlotte, race against time to find the killer, a treacherous mystery unfolds. And no one, not the lowest brand of ruffian or the most established aristocrat, will escape unscathed.