An epic historical adventure story set in a Jewish shtetl during the final years of the Russian Empire, The Slaughterman's Daughter follows Fanny Keismann on her quest to avenge her sister's honour. When Fanny Keismann turns ten, her father, Grodno's ritual slaughterer, gives her a knife, and she soon develops a talent for her father's trade. But in nineteenth-century Russia, ritual slaughter does not befit a wife and mother, so when it comes time to marry and raise a family, Fanny abandons her work and devotes herself to raising her five children. When Fanny's older sister's husband disappears, Fanny leaves her own family and sets out for the great city of Minsk in search of her wayward brother-in-law, armed with her old knife and accompanied by Zizek Bershov, who is either a sly rogue or an idiot. Fanny's mission to help her sister turns into a misadventure that threatens the foundations of the Russian Empire. What began as a family matter in Motol, a peripheral Jewish settlement, breaks the bounds of the shtetl, pits the police against the Czar's army, and upsets the political and social order they all live in.