New York City's super-crime landscape has been a ticking time bomb, and now it finally explodes! What incites the Gang War?! Who hired Shotgun and took out Tombstone? And what, if anything, can Spider-Man do about it? As NYC becomes an open battlefield for a ruthless super-villain conflict, the wall-crawler will need an amazing team. But which side will the injured Tombstone take in this war? And will Wilson Fisk, the former Kingpin of Crime, sit this one out? Don't bet on it! The biggest and most brutal battle in Spidey history is about to play out. And if you thought you knew what Madame Masque, Hobgoblin, Beetle or Diamondback were capable of, think again!