Welcome to the House of Dahomey, the houseboat of Erzulie Freda, where the souls of Voodoo followers go when they sleep but even the fearsome Erzulie is powerless when her dream river turns sour, tossing her house from one realm and into another.. the Dreaming! From her bayou, Erzulie scries upon the mortal realm and sees four human girls open a mysterious and magical journal filled with whispers and rumors that, if they spread, could cause a pandemic unlike any the Earth has seen, with the power to release Shakpana, the loa lord of infectious disease and nephew to Erzulie, who is currently banned from the human plane. Meanwhile, a mysterious infection doctors are calling "Cotard's Delusion" spreads, trapping countless souls in the Dreaming and leaving their physical bodies yearning for death.